Sucralfate and Oxetacaine Suspension

Krafet-O is a potent and effective oral suspension combining Sucralfate and Oxetacaine, specifically designed for the treatment of gastrointestinal conditions involving mucosal damage – including gastric ulcers, duodenal ulcers, esophagitis, and severe gastroesophageal reflux disease (GERD). Manufactured by Pacitora Biotech, this formulation addresses both the root cause of ulcer pain (acid exposure) and the symptoms (burning sensation) simultaneously.

Sucralfate is a unique cytoprotective agent. Upon reaching the stomach, it undergoes a chemical transformation to form a viscous, adhesive gel that binds selectively to ulcerated tissues – not healthy ones. This protective barrier prevents further attack by gastric acid, pepsin, and bile salts, allowing the body’s natural healing processes to repair the damaged mucosa. Sucralfate remains active for up to six hours after each dose, providing sustained protection.

Oxetacaine (also known as Oxethazaine) is a potent topical anesthetic with a high safety margin. It rapidly numbs the gastric mucosa, providing quick relief from the intense burning pain associated with ulcers, gastritis, and acid reflux. Unlike systemic painkillers, oxetacaine works locally without affecting the central nervous system. Its effects begin within minutes of ingestion, offering patients much-needed comfort while sucralfate works on long-term healing.

Key Benefits:

• Forms Protective Barrier – Sucralfate adheres to ulcers and erosions, shielding them from acid and enzymes.

• Rapid Pain Relief – Oxetacaine provides fast-acting local anesthesia to soothe burning pain.

• Neutralizes Acid Effects – Helps reduce the damaging impact of gastric acid on the stomach lining.

• Promotes Ulcer Healing – Creates an optimal healing environment for gastric and duodenal ulcers.

• Effective for GERD – Relieves heartburn, acid reflux, and epigastric discomfort.

FAQs:

1. When should I take Krafet-O for best results?
Take it on an empty stomach, at least one hour before meals and at bedtime, as food can interfere with sucralfate’s binding to ulcers.

2. How quickly does Krafet-O relieve ulcer pain?
Oxetacaine provides noticeable relief within 5 to 10 minutes, while sucralfate takes several days to weeks to heal the ulcer completely.

3. Can I take Krafet-O with antacids or other medications?
Antacids and many other drugs should be taken at least 30 minutes before or 2 hours after Krafet-O to prevent reduced effectiveness.

4. Are there any common side effects of Krafet-O?
The most common side effects are mild constipation (due to sucralfate) or transient dizziness (rare from oxetacaine) – both usually resolve on their own.