Paracetamol & Mefenamic Acid Suspension

Pacipra-MF is a specially formulated oral suspension combining Paracetamol and Mefenamic Acid – two well-established analgesics and antipyretics that work synergistically to provide comprehensive relief from pain, fever, and inflammation. Manufactured by Pacitora Biotech – a brand committed to “Accelerating Healthcare for All” – Pacipra-MF offers a convenient, easy-to-swallow liquid formulation ideal for patients of all ages, particularly children and the elderly who may struggle with tablets or capsules.

Paracetamol (Acetaminophen) – As one of the most widely used antipyretic (fever-reducing) and analgesic (pain-relieving) agents worldwide, paracetamol works by inhibiting cyclooxygenase (COX) enzymes in the brain. It effectively lowers elevated body temperature by acting on the hypothalamic heat-regulating center and raises the pain threshold without causing significant gastric irritation. Paracetamol is the first-line choice for fever management in both adults and children.

Mefenamic Acid – Belonging to the non-steroidal anti-inflammatory drug (NSAID) class, mefenamic acid works by inhibiting both COX-1 and COX-2 enzymes, thereby reducing the production of prostaglandins – chemical messengers responsible for pain, inflammation, and fever. Unlike paracetamol alone, mefenamic acid provides additional anti-inflammatory benefits, making it particularly effective for:

• Dysmenorrhea (painful menstrual cramps) – Prostaglandin inhibition directly relieves uterine muscle spasms.

• Musculoskeletal pain – Sprains, strains, and arthritis flare-ups.

• Dental pain – Toothaches and post-extraction pain.

• Post-surgical and trauma-related pain – Reduces both pain and associated swelling.

Key Benefits:

• Reduces Fever – Paracetamol acts on the brain’s temperature regulation center to bring down fever quickly.

• Relieves Pain – Effective against headaches, toothaches, body aches, and post-surgical pain.

• Fights Inflammation – Mefenamic acid provides anti-inflammatory action for swollen joints and tissues.

• Eases Menstrual Cramps – Particularly effective for dysmenorrhea (painful periods).

• Suspension Formulation – Easy to swallow and ideal for children, elderly, and those who cannot take tablets.

FAQs:

1. How quickly does Pacipra-MF work for fever?
Paracetamol typically begins reducing fever within 30 to 60 minutes, with maximum effect seen around 1 to 2 hours after taking the dose.

2. Can Pacipra-MF be taken on an empty stomach?
It is best taken with or after food to minimize the risk of gastric irritation – especially important due to the mefenamic acid component.

3. Is Pacipra-MF safe for children?
Yes, but only under pediatric guidance. The dosage must be strictly calculated based on the child’s weight and age. Never exceed the prescribed dose.

4. Can I take Pacipra-MF during menstruation?
Yes, it is highly effective for menstrual cramps (dysmenorrhea) due to mefenamic acid’s direct action on uterine prostaglandins. Start at the first sign of pain.