Enteric Coated Rabeprazole Sodium and Levosulpiride SR Capsules

PACTORAB-LS is an advanced, dual-action capsule formulation by Pacitora Biotech that combines Enteric Coated Rabeprazole Sodium (a fast-acting Proton Pump Inhibitor – PPI) and Levosulpiride SR (a unique prokinetic agent with additional anxiolytic properties). This powerful combination is specifically designed for patients suffering from gastroesophageal reflux disease (GERD) , especially when associated with stress, anxiety, or depression; functional dyspepsia (indigestion with bloating and early satiety); irritable bowel syndrome (IBS) ; gastroparesis (delayed gastric emptying); and chronic nausea and vomiting.

Key Benefits:

• Fast-Acting Acid Suppression – Rabeprazole (enteric coated) reduces gastric acid rapidly – fastest onset among PPIs.

• Unique Prokinetic and Anxiolytic – Levosulpiride improves gastric emptying AND helps manage stress-related digestive symptoms.

• Effective for GERD with Anxiety – Specifically beneficial when acid reflux is triggered or worsened by stress and anxiety.

• Improves Gastric Emptying – Levosulpiride enhances gut motility, reducing bloating, fullness, and nausea.

• Relieves Nausea and Vomiting – Powerful anti-emetic action through dopamine D2 receptor blockade.

• Helps Manage IBS – Levosulpiride is effective for irritable bowel syndrome (especially with predominant bloating).

FAQs:

1. What makes Pactorab-LS different from regular Rabeprazole and Domperidone combinations?
Levosulpiride is a unique prokinetic that also has anxiolytic (anti-anxiety) properties – making it especially effective for stress-related GERD, functional dyspepsia, and IBS, unlike domperidone which only addresses motility.

2. Can Pactorab-LS help with bloating and early fullness after meals?
Yes – levosulpiride is highly effective for functional dyspepsia, specifically improving gastric accommodation and emptying, which reduces post-meal bloating, fullness, and discomfort.

3. Is Levosulpiride safe for long-term use?
At the low doses used for GI disorders (typically 25-50 mg twice daily), levosulpiride has a good safety profile with low risk of extrapyramidal symptoms, unlike metoclopramide. Use under medical supervision.

4. Can I take Pactorab-LS if I have anxiety but no digestive issues?
No – Pactorab-LS is indicated for digestive disorders. The anxiolytic effect of levosulpiride at GI doses is mild and primarily benefits patients whose digestive symptoms are triggered or worsened by stress.